Search on: CHANNEL, ERG1 POTASSIUM 
Descriptors Found: 1
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Descriptor English:   ERG1 Potassium Channel 
Descriptor Spanish:   Canal de Potasio ERG1 
Descriptor Portuguese:   Canal de Potássio ERG1 
Synonyms English:   Ether-A-Go-Go-Related Potassium Channel 1
Kv11.1 Protein-Potassium Channel
Potassium Voltage-Gated Channel, Subfamily H, Member 2
Channel, ERG1 Potassium
Channel, Kv11.1 Protein-Potassium
Ether A Go Go Related Potassium Channel 1
Kv11.1 Protein Potassium Channel
Potassium Channel, ERG1
Protein-Potassium Channel, Kv11.1  
Tree Number:   D12.776.157.530.400.600.900.249.500
D12.776.543.550.450.750.900.249.500
D12.776.543.585.400.750.900.249.500
Definition English:   One of three members of the ether-a-go-go (EAG) POTASSIUM CHANNELS gene family comprising ether-a-go-go (eag), eag-like (elk) and eag-related (erg) subfamilies. Ether-a-go-go-related gene 1 (ERG1) also known as KCNH2, encodes the pore-forming subunit of a rapidly activating-delayed rectifier potassium channel that plays an essential role in the final repolarization of ventricular action potential. Loss-of-function mutations in human hERG1 is associated with life-threatening ARRHYTHMIA. 
History Note English:   2017 (2001) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   56585 
Unique Identifier:   D000072237 

Occurrence in VHL: 		 

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